Sydney Parham Epes (August 20, 1865 - March 3, 1900) was a U.S. Representative from Virginia, cousin of James F. Epes and William Bacon Oliver.
Born near Nottoway Court House, Virginia, Epes moved with his parents to Kentucky and settled near Franklin, Kentucky, where he attended the public schools. He returned to Virginia in 1884 and edited and published a Democratic newspaper at Blackstone, Virginia. He served as member of the Virginia House of Delegates in 1891 and 1892. He served as register of the Virginia land office from 1895–1897, and presented credentials as a Member-elect to the Fifty-fifth Congress and served from March 4, 1897, until March 23, 1898, when he was succeeded by Robert T. Thorp, who contested the election.
Epes was elected as a Democrat to the Fifty-sixth Congress and served from March 4, 1899, until his death in Washington, D.C., March 3, 1900. He was interred in Lake View Cemetery, Blackstone, Virginia.